High fructose induced osteogenic differentiation of human valve interstitial cells via activating PI3K/AKT/mitochondria signaling
Background: Aortic valve stenosis (AS) is a common, lethal cardiovascular disease.There is no cure except the valve replacement at last stage.Therefore, an understanding of the detail mechanism LED Bulb is imperative to prevent and intervene AS.Metabolic syndrome (MetS) is one of the major risk factors of AS whereas fructose overconsuming tops the